Here are just a few of the interesting things I gleaned from Dr. Hill’s lecture: (Trying not to be too technical, but this stuff is cool!)
1. The market is flooded with CDB (cannabidiol) containing products, from facial creams to doggy treats. The rush to become a leader has driven many manufacturers/suppliers to produce inconsistent levels of purity and therefore effectiveness. Additionally, from the FDA: “[S]ome companies are marketing products containing cannabis and cannabis-derived compounds in ways that violate the Federal Food, Drug and Cosmetic Act (FD&C Act) and that may put the health and safety of consumers at risk.” Be careful, some CBD oils on the market contain SIGNIFICANT levels of THC and could trigger a psychoactive response and/or positive drug test.
2. The regulatory agencies have stated that products with less than .3% THC can be called “hemp” and are not subject to controlled substance regulations. However, there is no such thing as “zero THC” in the products on the market today. Be careful!
3. Although CBD does not have the same psychoactive properties as THC, it does “directly” interact with CB1 and CB2 receptors, but the direct interaction is so weak that it is of no consequence. Instead, it affects the body through an “indirect” mechanism. It acts on a fatty acid that breaks down a “good” endocannabinoid called anandamide. CBD slows down the fatty acid’s activity which leads to an increase in the level of anandamide in the body. (Anandamide is an endocannabinoid the body makes which affect both CB1 and CB2 receptors, resulting in feelings of euphoria (CB1) and soothing of inflammation in tissues (CB2).)
4. One of the primary constituents in Copaiba, Beta- caryophyllene (about 55%, the highest of any known oil), is a DIRECT activator of CB2 and has no interaction with CB1. Additionally, the synergy of the various other constituents (copaene, bergamotene, and humulene) in Copaiba provides other significant benefits, including support for immune systems function, antioxidant function, and proper inflammatory response.
The science is being developed as we speak, but it is clear that Copaiba is much more than the sum of its parts. If you’re deciding between a chemical isolate (CBD) or a whole oil, nature’s formulation is the clear choice.